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Seann Mulcahy

Associate Professor

Contact Information:

smulcahy@providence.edu

401.865.1280

Albertus Magnus Hall 319

Education:

Postdoctoral Research - Yale University (2010) and Boston University (2012)

Ph.D. - University of Pennsylvania (2009)

B.S. - University of Richmond (2004)

Area(s) of Expertise:

Organic chemistry, medicinal chemistry, chemical biology, chemical education

Selected Publications:

Saliba, B. Khanal, S. O’Donnell, M. Queenan, K. Song, J. Gentile, M. Mulcahy, S. (2018) Parallel strategies for the synthesis of annulated pyrido[3,4-b]indoles via Rh(1)- and Pd(0)-catalyzed cyclotrimerization. Tetrahedron Letters.(59), 4311-4314.

Giulietti, J. Tate, P. Cai, A. Cho, B. Mulcahy, S. (2016) DNA-binding studies of the natural product eudistomin U. Bioorganic and Medicinal Chemistry Letters.(26), 4705-4708.

Mulcahy, S. Varelas, J. Khanal, S. O'Donnell, M. (2015) Concise Synthesis of Annulated Pyrido[3,4-b]indoles via Rh(I)-Catalyzed Cyclization. Organic Letters.(17), 5512-5514.

Roggero, C. Giulietti, J. Mulcahy, S. (2014) Efficient synthesis of eudistomin U and evaluation of its cytotoxicity. Bioorganic and Medicinal Chemistry Letters.(24), 3549-3551.

Mulcahy, S. Varelas, J. (2013) Three-step synthesis of an annulated β-carboline via palladium catalysis. Tetrahedron Letters.(54), 6599-6601.

Mulcahy, S. Woo, C. Ding, W. Ellestad, G. Herzon, S. (2012) Characterization of a Reductively-Activated Elimination Pathway Relevant to the Biological Chemistry of the Kinamycins and Lomaiviticins. Chemical Science.(3), 1070-1074.

Mulcahy, S. Gruendler, K. Frias, C. Prokop, A. Meggers, E. (2010) Discovery of a Strongly Apoptotic Ruthenium Complex Through Combinatorial Coordination Chemistry. Dalton Transactions.(39), 8177-8182.

Gong, L. Mulcahy, S. Harms, K. Meggers, E. (2009) Chiral-Auxiliary-Mediated Asymmetric Synthesis of Tris-Heteroleptic Ruthenium(II) Polypyridyl Complexes. Journal of the American Chemical Society.(131), 9602-9603.

Selected Presentations:

Mulcahy, S. Roggero, C. Giulietti, J. Thomas, S. 248th National Meeting of the American Chemical Society. American Chemical Society, San Francisco, CA - "Suzuki Cross Coupling Strategy for the Synthesis of 1-Aryl and 1-Heteroaryl Eudistomin U Analogs" August, 2014

Varelas, J. O'Donnell, M. Khanal, S. Mulcahy, S. 247th National Meeting of the American Chemical Society. American Chemical Society, Dallas, TX - "Convenient synthesis of annulated β-carbolines via transition metal-catalyzed [2+2+2] cyclization" March, 2014

Schwarzer, C. Szeto, H. Gale-Day, Z. Snyder, J. Mulcahy, S. 247th National Meeting of the American Chemical Society. American Chemical Society, Dallas, TX - "Diastereoselective synthesis of unnatural alkaloids" March, 2014

Roggero, C. Giulietti, J. Mulcahy, S. 247th National Meeting of the American Chemical Society. American Chemical Society, Dallas, TX - "Synthesis of β-carboline natural products via divergent palladium catalysis" March, 2014

Giulietti, J. Roggero, C. Mulcahy, S. 247th National Meeting of the American Chemical Society. American Chemical Society, Dallas, TX - "Synthesis, cytotoxicity, and DNA-binding studies of the natural product eudistomin U" March, 2014