Seann Mulcahy


Contact Information:


Science Complex 02-20


Postdoctoral Research - Yale University (2010) and Boston University (2012)

Ph.D. - University of Pennsylvania (2009)

B.S. - University of Richmond (2004)

Brief Biography:

I grew up outside of Albany, New York and attended the University of Richmond for my undergraduate training in chemistry and to participate in cross country/track and field. I conducted research in organic chemistry and had such great mentorship from the faculty that I knew my calling was to teach and do research at a primarily undergraduate institution. After graduate school and a few postdocs, I came to PC to fulfill my dream of training the next generation of scientists to solve the world's greatest problems. In my spare time, I like to run, swim, bike, and hike.

Area(s) of Expertise:

Organic chemistry, Medicinal chemistry, NMR spectroscopy

Teaching Philosophy:

The goals of the courses I teach are often directly aligned with the values of liberal education: teaching students not what to think, but how to think, so that they may become enthusiastic, lifelong learners and responsible, world-conscious citizens on whatever path they choose in life. I believe that the conditions that foster the best learning environment are the ones in which students develop higher-order skills that allow them to solve problems they have never seen before. The most important skills we can teach students are how to reason analytically, make compelling arguments, interpret data objectively, communicate effectively, and search for something they do not know, tools that they will use continuously throughout their lives.

Selected Publications:

Medas, K. Lesch, R. Edioma, F. Ndahayo, V. Wrenn, S. Mulcahy, S. (2020) Metal-Catalyzed Cyclotrimerization Reactions of Cyanamides: Synthesis of 2-Aryl-alpha-carbolines. Organic Letters.(22), 3135-3139.

Foley, C. Al-Issa, Y. Hiller, K. Mulcahy, S. (2019) Synthesis and Structure-Activity Relationships of 1-Aryl-beta-carbolines as Affinity Probes for the 5-Hydroxytryptamine Receptor. ACS Omega.(4), 9807-9812.

Saliba, B. Khanal, S. O’Donnell, M. Queenan, K. Song, J. Gentile, M. Mulcahy, S. (2018) Parallel strategies for the synthesis of annulated pyrido[3,4-b]indoles via Rh(1)- and Pd(0)-catalyzed cyclotrimerization. Tetrahedron Letters.(59), 4311-4314.

Giulietti, J. Tate, P. Cai, A. Cho, B. Mulcahy, S. (2016) DNA-binding studies of the natural product eudistomin U. Bioorganic and Medicinal Chemistry Letters.(26), 4705-4708.

Mulcahy, S. Varelas, J. Khanal, S. O'Donnell, M. (2015) Concise Synthesis of Annulated Pyrido[3,4-b]indoles via Rh(I)-Catalyzed Cyclization. Organic Letters.(17), 5512-5514.

Roggero, C. Giulietti, J. Mulcahy, S. (2014) Efficient synthesis of eudistomin U and evaluation of its cytotoxicity. Bioorganic and Medicinal Chemistry Letters.(24), 3549-3551.

Mulcahy, S. Varelas, J. (2013) Three-step synthesis of an annulated β-carboline via palladium catalysis. Tetrahedron Letters.(54), 6599-6601.

Detailed CV